(Senior) Research Scientist – Molecular and Cell Biology

AstraZeneca (AZ) is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. But we’re more than one of the world’s leading pharmaceutical companies. At AZ, we’re proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives – and are made to feel valued, energized and rewarded for their ideas and creativity.

Do you have a background in biochemistry or cell biology, aren’t afraid of trying new paths and doing things differently? Do you also feel passionate about the possibilities of science to change lives? Perfect, your next challenge might be this role at AstraZeneca!

Om tjänsten
A position has arisen for a highly motivated (Senior) Research Scientist – Molecular and Cell Biology to join the Cell and Molecular Pharmacology (CMP) team within the Early Cardiovascular, Renal and Metabolic (CVRM) disease area in Gothenburg, Sweden.

Early CVRM is one of three main therapeutic research areas within AstraZeneca that deliver candidate drugs into late-stage clinical development. The CMP team delivers key data based on histology, imaging, biomarker, FACS and bioassay automation to support projects across the Cardiovascular, Renal and Metabolism disease areas.

Dina arbetsuppgifter i huvudsak
The role is lab-based, providing dedicated experimental support to our drug discovery programs. The successful candidate will deliver high-quality molecular biology data to build a detailed understanding of pharmacological response and mode of action for small molecules, PROTACs and ASOs. The work includes independent planning and execution of experiments, troubleshooting and timely reporting/presentation of data according to agreed timelines.

Vem är du?
Essential Requirements:
• BSc/MSc degree in Molecular Biology, Biomedical, Pharmacology, Biochemistry or a related discipline with significant practical experience.
• Extensive experience in molecular and cellular biology techniques including protein and gene expression analysis, Western Blot, qPCR and cell culture. Ideally applied to relevant cellular assays and in vivo samples.
• Excellent communication skills and an ability to operate in a multi-disciplinary research environment.
• Independent analysis and evaluation of complex data and delivery of data to agreed timelines.

Desirable Experiences and Abilities:
• Experience within Cardiovascular, Renal and/or Metabolic disease areas.
• Expertise in the design, development and validation of assays for compound profiling.
• Experience in flow cytometry.
• Experience working with PROTACs and/or antisense oligonucleotides (ASOs) in Mode of Action studies and pharmacological profiling.
• Proven ability in providing technical leadership and guidance to others.
• Scientific visibility and leadership through project contributions and scientific publications.

The successful candidate demonstrates a passion for driving scientific questions through experimental work, combined with strong team working ethics. You have good social and communication skills, is collaborative and a great team player. You should also be able to work independently and have a positive, goal oriented and problem-solving attitude. Excellent English is required, both spoken and written, and good organizational skills are of use.

Om verksamheten
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status or any other characteristic protected by law.