(Senior) Research Scientist – Molecular and Cell Biology

Do you have a background in biochemistry or cell biology, aren’t afraid of trying new paths and doing things differently? Do you also feel passionate about the possibilities of science to change lives? Perfect, your next challenge might be this role at AstraZeneca! 

A position has arisen for a highly motivated (Senior) Research Scientist – Molecular and Cell Biology to join the Cell and Molecular Pharmacology (CMP) team within the Early Cardiovascular, Renal and Metabolic (CVRM) disease area in Gothenburg, Sweden. Early CVRM is one of three main therapeutic research areas within AstraZeneca that deliver candidate drugs into late-stage clinical development. The CMP team delivers key data based on histology, imaging, biomarker, FACS and bioassay automation to support projects across the Cardiovascular, Renal and Metabolism disease areas.

The role is lab-based, providing dedicated experimental support to our drug discovery programs. The successful candidate will deliver high-quality molecular biology data to build a detailed understanding of pharmacological response and mode of action for small molecules, PROTACs and ASOs. The work includes independent planning and execution of experiments, troubleshooting and timely reporting/presentation of data according to agreed timelines.

ESSENTIAL REQUIREMENTS:
• BSC/MSC DEGREE IN MOLECULAR BIOLOGY, BIOMEDICAL, PHARMACOLOGY, BIOCHEMISTRY OR A RELATED DISCIPLINE WITH SIGNIFICANT PRACTICAL EXPERIENCE.
• EXTENSIVE EXPERIENCE IN MOLECULAR AND CELLULAR BIOLOGY TECHNIQUES INCLUDING PROTEIN AND GENE EXPRESSION ANALYSIS, WESTERN BLOT, QPCR AND CELL CULTURE. IDEALLY APPLIED TO RELEVANT CELLULAR ASSAYS AND IN VIVO SAMPLES.
• EXCELLENT COMMUNICATION SKILLS AND AN ABILITY TO OPERATE IN A MULTI-DISCIPLINARY RESEARCH ENVIRONMENT.
• INDEPENDENT ANALYSIS AND EVALUATION OF COMPLEX DATA AND DELIVERY OF DATA TO AGREED TIMELINES.

DESIRABLE EXPERIENCES AND ABILITIES:
• Experience within Cardiovascular, Renal and/or Metabolic disease areas.
• Expertise in the design, development and validation of assays for compound profiling.
• Experience in flow cytometry.
• Experience working with PROTACs and/or antisense oligonucleotides (ASOs) in Mode of Action studies and pharmacological profiling.
• Proven ability in providing technical leadership and guidance to others.
• Scientific visibility and leadership through project contributions and scientific publications.

The successful candidate demonstrates a passion for driving scientific questions through experimental work, combined with strong team working ethics. You have good social and communication skills, is collaborative and a great team player. You should also be able to work independently and have a positive, goal oriented and problem-solving attitude. Excellent English is required, both spoken and written, and good organizational skills are of use.

ABOUT ALTEN
Every employee is equally valuable in the success of ALTEN! We are driven by making people grow and develop, which is why we offer you the opportunity to work with what you are truly passionate about. At ALTEN, we have a broad range of assignments at most of the leading companies in Sweden in several different sectors, to make it possible for your wishes to come true. We offer both national and international opportunities and together with your coaching manager, you build your career path so you constantly are able to develop and achieve your goals and dreams! As a consultant at ALTEN, you will get the genuine team feeling at your assignment but also a wonderful togetherness at ALTEN. Through our different internal networks, such as ALTEN Sports, Women@ALTEN and ALTEN Innovation you will get the opportunity to drive topics and activities that are close to your heart, together with your colleagues. All activities are of course optional. Work life balance is our top priority. We also have a collective agreement and other benefits like Pension, Insurances and Wellness grants.

 

We believe in growing together!