Senior Scientist - Analytical Chemistry / Mass Spectrometry

Do you have a strong background in Mass Spectrometry and expertise in the characterization of small molecules and/or peptides, oligonucleotides and their conjugates? Do you want to join a place where our teamwork and collaborative atmosphere drives us forward? If yes, welcome to AstraZeneca!

We are looking for an enthusiastic MS expert, to join our team as a Senior Scientist, in the Therapeutic Area Respiratory and Immunology (R&I). This role is placed at AstraZeneca's vibrant R&D site in Gothenburg, Sweden.

The Physical and Analytical Chemistry team at R&I Medicinal Chemistry is working with a strong research focus to deliver Small Molecule (SM) and New Modalities (NM) drug candidates. The analytical team is operating in close collaboration with Medicinal Chemists and scientists in neighboring departments with a joint aim of discovery of the respiratory medicines of the future.

What you'll do
This is a lab based role in a team of analytical experts (LC-MS and NMR) supporting the Medicinal Chemistry of Small Molecules and New Modalities in early drug discovery. The daily work in this role includes hands-on operation of LC-HRMS instruments and evaluation/processing of analytical data with the aim to support early drug discovery projects with state-of-the-art analytics. Based on your thorough LC-MS competence, you will support the drug pipeline with a variety of applications from high-throughput compound library analysis to in-depth characterization of in-vivo and tox batches.


Typical accountabilities in your daily work:
* Efficient advancement of AZ drug discovery portfolio by applying LC-HRMS methods
* Driving internal build of analytical methodology for both small molecule and new modality compounds
* Effective collaboration with project team members and colleagues in Medicinal Chemistry and DMPK departments



We look forward to a new colleague with a problem-solving mindset and innovative approaches to complex scientific questions. You work independently, but you also enjoy teamwork and collaboration and can communicate well across functional boundaries.



Essential for the role
* PhD in Analytical Chemistry or equivalent professional experience from industry
* Significant and documented expertise in chemistry and mass spectrometry
* Demonstrated expertise in MS characterization of small and/or large synthetic molecules by MS/MS
* Experience and knowledge of separation techniques beyond RP-UPLC is a plus
* Experience from a variety of MS fragmentation techniques, digitalization of analytical workflows and automation is desirable


Why AstraZeneca?
There are many opportunities to develop yourself and your career. From our diverse portfolio and teamwork to our cutting-edge innovations - it's a place for lifelong learning. Ultimately, it's more than a job. We know that our work impacts people with serious conditions, many of whom have no other alternatives. That's what drives us - the potential to impact over one billion patients worldwide.



So what's next?
If this sounds like the next challenge for you, apply today!
We look forward to your application (including CV and cover letter). Please send it to us no later than June 30, 2022.

For more information about the position please contact hiring manager Tomas Leek, Team Leader, Physical and Analytical Chemistry, by email: Tomas.Leek(@)astrazeneca.com or via LinkedIn.


Additional information
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Make a move to Global Gothenburg: https://www.youtube.com/watch?v=c-Iqbb4aw38
Relocate to Gothenburg: https://www.astrazeneca.se/om-oss/verksamheten-i-sverige/goteborg/relocate-to-gothenburg.html
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html