Senior Scientist, Biomarker Discovery, Gothenburg, AstraZeneca

Job description
Senior Scientist, Biomarker Discovery and Development
Do you have expertise in Biomarker Discovery and Development in Cardiovascular, Metabolic and Renal Diseases? Would you like to apply your expertise at a company that are following the science and turn ideas into life changing medicines? If this matches your ambition and skills, then you might be the one we are looking for!
We are now recruiting a Senior Scientist, Biomarker Discovery and Development to join the Biomarker team in the department of Translational Science and Experimental Medicine (TS&EM) within Early Cardiovascular Renal and Metabolic Diseases (CVRM) therapeutic area at AstraZeneca in Gothenburg, Sweden.
Early Cardiovascular, Renal and Metabolism (CVRM) is accountable for the discovery and development (up to phase II) of new medicines within three main strategic areas - cardiovascular/heart failure, metabolism (diabetes and NASH) and chronic kidney disease. The Translational Sciences and Experimental Medicine (TS&EM) Department within Early CVRM has the remit to bridge early and late drug development by providing: i) target validation in humans; ii) biomarker strategy (target engagement & proof of mechanism biomarkers); iii) precision medicine strategies; and iv) human data-driven novel target identification. Biomarker team delivers high-quality biomarker assays for assessment of target engagement and proof-of-mechanism as well as for precision medicine hypothesis generation from in vitro and in vivo models up to patients.

Responsibilities
What you’ll do
As a Biomarker Scientist, you will be a key member in the Biomarker Discovery and Development team and play a key role from preclinical to clinical biomarker delivery for progressing projects and science. This role will be primarily lab based and contribute to building the biomarker strategy i.e., driving biomarker discovery for identification of target-related biomarkers and for precision medicine hypothesis generation. You will be responsible for delivering high quality and robust biomarker data package to support project progression across the CVRM project portfolio. This involves implementation of novel biomarker methods e.g. mass spectrometry-based approaches using state of the art analytical techniques, biomarker analysis, reporting biomarker data and evaluation to the project teams. Collaboration is critical for successful delivery of drug projects and you will work closely with scientists/teams from a wide range of different functions within AstraZeneca. In this role, you will have the opportunity to try novel techniques and ideas for identification of new biomarkers.

Qualifications
Essential for the role
PhD or equivalent education in analytical chemistry or related scientific discipline
A solid background in the field of analytical chemistry with focus on various immunoassays platforms as well as liquid chromatography and mass spectrometry.
Expertise in analyzing endogenous biomarkers using immunoassay platforms (ELISA, MSD, Luminex, SIMOA, Clinical analyzers)
Expertise in quantitatively analyzing endogenous biomarkers such as polar metabolites, lipids, peptides and proteins using liquid chromatography mass spectrometry
Hands on research experience of ex vivo work on urinary extracellular vesicles and various blood cell populations
Ability to plan and report all work to appropriate standards (Good Laboratory Standard, GLS)
Good project management and matrix leadership skills, ability to collaborate well cross functions
Passion for delivering and promoting excellence in science.
Excellent English communication skills, both verbal and written


Application
Deadline: 2022-10-28, selection and interviews will be ongoing. 
The position may be filled before the last day of application, therefore, apply as soon as possible. 

For more information: 
Please contact Katan Ali, 
katan.ali@randstad.se

About the company
About randstad life sciences 
Randstad Life Sciences is specialized in competencies within Life Science. As a consultant with us, you get a competitive salary, benefits, and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many activities.

With more than 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry and offers staffing, consulting and recruitment solutions in all areas of expertise. We also offer interim management, executive search and outplacement services. We have a broad network of clients and candidates, which means we convey hundreds of jobs within different industries all over Sweden. Our ambition is to be the best employer in the market.

By combining our passion for people with the power of today’s technology, we help people and organizations to reach their true potential. We call it Human Forward.