Senior Scientist - Downstream Process Development

Senior Scientist - Downstream Process Developmen

Do you drive activities independently and proactively? Do you have a flexible, creative, pragmatic and collaborative approach at work? Do you turn challenges into opportunities? Are solidarity and togetherness important for you to perform at your best?

The position as Downstream Senior Scientist at Xbrane Biopharma, is an opportunity to join an innovative and growing team within the development of Biosimilars. You will have the possibility to be part of the process development team and ensure the access of biologics to an underserved patient population, enabling global health equality, by developing strategies for drug substance and drug product development for biosimilars. You will provide technical expertise and support as needed with external partners, e.g. to CMOs during clinical and commercial manufacturing as well as support the Regulatory Affairs team with input to regulatory filings such as INDs, IMPDs and market applications. You will also be responsible for:

• Coordinating and developing midstream and downstream processes for Drug Substance for Xbrane’s Biosimilars.
• Drug Substance and Drug Product process transfer from development to manufacturing.
• Supporting experimental work and writing for patent applications.
• Streamline overall workflow in Drug Substance and Drug Product process development at Xbrane, to ensure an improved and more efficient biosimilar product development process.

Qualification:

• BSc, MSc or PhD degree in Life Sciences or related field, depending on experience.
• Experience in midstream processing of mammalian and microbial cultures such as depth filtration, tangential flow filtration, and continuous centrifugation.
• Extensive experience in downstream processing of mammalian and microbial cultures such as purification using affinity, ion exchange, multimodal and hydrophobic interaction chromatography, viral inactivation and nanofiltration.
• Extensive experience in design of experiments (DoE).
• Experience in other biochemical techniques such as SDS-PAGE, Native-PAGE, western blotting, ELISA.
• Experience in project coordination and supervision of junior colleagues.
• Experience in Drug Product development, process transfer to external partners and regulatory filing is advantageous.

The individual must be highly motivated, flexible, creative and organized. The individual must be able to plan and work independently, but also, work in the lab, collaboratively. We are looking for a team player with excellent oral and written communication skills.

Xbrane is a Great Place to Work certified company that offers an opportunity to grow in your professional role, as well as the opportunity to influence and further develop the company as a whole alongside a highly competent team.

If you have a can-do attitude and on top of that share our values, Make it happen, Beat yesterday, Impossible is nothing and We win as one, you will prosper with us.

Interested?
In this recruitment, Xbrane is collaborating with Mpya Sci & Tech.

Please submit your application no later than the 23th of October. Interviews will be scheduled continuously. Questions? Please contact Johan Östman, +46(0)76 628 78 91 or johan.ostman@mpyascitech.com

About Xbrane Biopharma

Xbrane Biopharma is a Swedish biotechnology company which develops and manufactures biosimilars. Xbrane has a patented protein production platform and world-leading expertise within biosimilar development. This is a Great Place to Work certified company with an entrepreneurial spirit that focuses on being creative and coming up with new ideas as well as on following a rigorous process to bring those ideas to fruition. Xbrane’s headquarter is located at Solna Campus, just outside of Stockholm, for more information see www.xbrane.com.