Senior Scientist, Formulation - Advanced Drug Delivery

At AstraZeneca, we unlock the power of What Science Can Do. Empowered to explore, every day we work towards our ultimate aim - treating, preventing, modifying and even curing complex diseases. Be part of the team where you are empowered to follow the science!

Pharmaceutical Sciences at AstraZeneca deliver the therapies of the future through scientific leadership in drug delivery, design of synthetic routes, and manufacturing of Active Pharmaceutical Ingredients (API) and drug products. Our portfolio of projects spans small molecules, peptides, oligonucleotides to RNA based therapeutics across AstraZeneca's therapy areas. Advanced Drug Delivery (ADD) resides within Pharmaceutical Sciences with a mission to provide novel products to AstraZeneca's clinical pipeline.

We now seek a talented and motivated Formulation Scientist or Senior Scientist (depending on your background and experience) to join the New Modality Clinical Formulation & Bioscience team within the ADD function in Gothenburg, Sweden.

This is an exciting role where you will act as a key member in various project teams to provide your expertise into formulation development and design within the new modality and advanced drug delivery portfolio of peptides, oligonucleotides and RNA based therapeutics, with emphasis on parental formulation development. You will contribute to developing and selecting lead enabling formulations and to defining drug product design to ensure desired clinical performance in projects spanning pre-clinical to Phase II development. Furthermore, the role covers contribution to regulatory submissions, coordination of GxP/non-GxP drug product manufacturing and outsourcing efforts, as well as involvement in internal and external scientific initiatives.

As such, we are looking for a candidate with previous experience in supporting formulation development of biomolecules (e.g., peptides, oligonucleotides, RNA), preferably in the clinical drug development phase, and who has knowledge of physical chemistry, biopharmaceutics and drug delivery to enable a mechanistic understanding of in vivo drug product performance. The role will be expected to work cross-functionally supporting drug projects from early to late clinical phase and in collaboration with other formulators, analysts, chemists and biologists at AstraZeneca in Sweden, UK and US.

Essential for the role

* MSc or PhD degree in a relevant scientific discipline (e.g., Pharmaceutics, Chemistry, Biotechnology or Biophysics)
* Experience of formulation development for different administration routes and of different formulation technologies
* Experience of working with biomolecules (e.g., peptides, proteins or nucleotide based molecules) and/or the desire to explore new modalities
* Ability to communicate and write proficiently in English

Desirable for the role

* PhD degree and post-doctoral experience in a relevant discipline (such as Pharmaceutics, Biopharmaceutics or Drug Delivery) or equivalent industrial experience within the field of Pharmaceutical/Biopharmaceutical Science
* Industrial experience of formulation work with biomolecules in clinical development phase
* Good understanding of the overall drug discovery and development process and an appreciation of how Pharmaceutical Sciences disciplines contribute to R&D
* Innovative, with a passion driving scientific excellence and a continuous improvement mindset

If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be.

With us there are many opportunities to develop yourself and your career. From our diverse portfolio and teamwork, to our cutting-edge innovations - it's a place for lifelong learning.

So, what's next?

Are you already imagining yourself joining us? Good, because we can't wait to hear from you!

For more information, please contact: Sara Richardson, Team Leader, +46725821650, sara.richardson@astrazeneca.com

Welcome with your application no later than February 4, 2021.

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

Additional information

BioPharmaceuticals R&D: https://www.youtube.com/watch?v=pmFx_jr2eFo

Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html

Life in Gothenburg: https://www.movetogothenburg.com/

Culture and atmosphere of the Gothenburg site: https://www.linkedin.com/feed/update/urn:li:activity:6496327311678410752/