Senior Scientist, Immune Cell Therapy, Non-oncology indications

Are you a cell biologist with a strong background in immunology and immune cell therapy? Are you excited by the opportunity to apply your scientific drive to the preclinical development of cell-based therapies for autoimmune diseases or regenerative medicine? Join us and be a key player in the build of our Biopharmaceuticals R&D Cell Therapy department. Together we will push the boundaries of Science!

At AstraZeneca, you will be empowered to be innovative and creative where difference is valued. We thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

Biopharmaceuticals R&D is committed to the development of next generation innovative medicines and we are building a new Cell Therapy department with the goal to establish AstraZeneca as a world-leader in Cell Therapy across disease areas within Cardiovascular, Renal and Metabolism (CVRM) and Respiratory and Inflammation (R&I). The department will bring together >50 specialists to support the organisation with cell therapy expertise and capabilities. The new department has an agile "biotech-like" culture, with specialists in the department working closely with experts across AstraZeneca globally to leverage the existing and emerging platforms in stem cell technologies, new modalities, universal cell lines, and CRISPR-mediated genome editing.

The role is placed at AstraZeneca's dynamic R&D site in Gothenburg, Sweden, where you will work in an international environment at the fore front of Cell Therapy science.

What you'll do

This role provide an opportunity to work in an international, highly cross disciplinary environment with ground breaking technologies within cell biology, immunology and precise genome editing.

As a skilled cell culture scientist, with a background in immunology and ideally its application in cell therapy of non-oncology indications, you will work collaboratively with project leaders, in vitro and in vivo scientists and therapy area specialists to ensure efficient progress of Cell Therapy projects. As a lab based scientist you will design experiments, deliver data and propose next steps in support of cell therapy projects. In addition, you will take a leading role in developing our scientific capabilities and presenting our novel work externally. Accountabilities include:

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Design and perform in vitro experiments to generate high quality, relevant data
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Independently assess and report data to support project decisions and milestones
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Apply critical and methodical thinking to interpret results and implement new strategies to advance cell therapy platform
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Communicate and share relevant information between distinct projects within the bioscience department as well as across other functions and also externally
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Keep up to date with relevant scientific literature and technology platforms as well as writing and publishing scientific papers
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Ensure that your work is compliant, to a high quality and in accordance with other relevant internal and external standards and regulations

Essential for the role

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Ph.D. in Cell Biology, Immunology or a related discipline, MSc degree with additional relevant academic or industrial experience may be considered
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Strong background in immunology with application in immune cell therapy, experience with T/CAR-T cells, NK cells or macrophages is desirable
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Proficiency in in vitro assays interrogating immune cell function, such as cellular activation/ suppression, cytokine release, proliferation, and killing assays
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Proficiency in multi-color flow cytometry, cell sorting and data analysis
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Good scientific presentation skills and ability to comfortably present and discuss scientific data.
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Excellent oral and written communication skills, a collaborative mindset, and a strong team player
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Ability to work independently, take own initiatives and have a positive, goal oriented and problem-solving attitude
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Excellent organizational, data management and documentation skills

Desirable for the role

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Experience in cell immunotherapy discovery
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Experience with gene engineering and gene editing
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Experience with stem and primary cell culture
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Knowledge of autoimmune diseases and regenerative therapy

So, what's next?

Are you already imagining yourself joining our team? Good, because we can't wait to hear from you!

Welcome with your application no later than November 7, 2021

Where can I find out more?

Cell Therapy Biopharmaceuticals R&D: Link

Our Gothenburg site: Link

Why AstraZeneca?

Our Gothenburg site is one of AstraZeneca's three strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to foster a working environment that nurtures, collaboration, openness and innovation. Therefore, we have created space for meetings, socializing and relaxation, where spontaneous meetings can give birth to new innovations. The unexpected ideas or thoughts that can come from a chat over something as simple as a cup of coffee or a stroll on our "walk and talk" meeting trail.