Senior Scientist in Advanced Drug Delivery

Are you a motivated Formulation Scientist with experience in cell/molecular biology? Do you want to be part of a team that works closely together to make a difference for patients' lives every day? If yes, this might be your next challenge!

At AstraZeneca we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.

Pharmaceutical Sciences at AstraZeneca delivers the therapies of the future through scientific leadership in drug delivery, design of synthetic routes, and manufacturing of Active Pharmaceutical Ingredients (API) and drug products. Our portfolio of projects spans small molecules, peptides, oligonucleotides to RNA-based therapeutics across AstraZeneca's therapy areas. Advanced Drug Delivery (ADD) resides within Pharmaceutical Sciences with a mission to transform diverse modalities into investigational medicines.

We are now looking for a skilled and experienced Formulation Scientist to join us as Senior Scientist in the New Modality Preformulation team. The role sits within the ADD group at our vibrant R&D site in Gothenburg, Sweden.

What you'll do:
This is an exciting role where you will act as a key member of various project teams and provide your technical and scientific expertise to engineer and test novel drug delivery systems for nucleotide-based therapeutics. This will involve formulating multiple delivery systems, notably nano-medicines, and testing them in vitro in cell culture. You will also work to improve the methods for doing this including laboratory automation, multivariate methods, data informatics and rapid prototyping will all be part of your job.

As such, we are looking for a candidate with experience in nano-medicine formulations and in vitro cell biology, preferably intracellular trafficking assays. The role will be expected to work cross-functionally supporting drug projects in early to late discovery and be involved in science & technology initiatives. You will also be expected to drive science networks and provide high quality scientific input across the organisation. We expect you to be an active member of the external scientific community enhancing our reputation as scientific leaders in the advanced drug delivery field.

We are looking for you, who together with your team will make a difference for patients' lives every day. This through your ability to independently lead and achieve set goals within budget, time and to the right quality.

Essential for the role:

* PhD degree in a relevant field (such as Pharmaceutical Science, Biotechnology, Cell Biology or related fields) and industrial or Postdoctoral experience within the field of Drug Delivery.
* Know-how regarding nano-medicine formulation, design and preparation, especially lipid nano-particles.
* Experience in cell/molecular biology and culturing and analysing different cell types.
* Technical aptitude and experience with instrumentation related to cell biology and formulation of nanomedicines.
* Excellent knowledge of endosomal biology.
* A good understanding of software for handling large multivariate datasets.
* Ability and desire/willingness to effectively communicate, network and build collaborative relationships with partners across disciplines and cultures, internally and externally and independently lead and influence projects.

Desirable for the role:

* Experience with laboratory automation including fluidic handling robots and automated analytical systems.
* Experience with composition optimisation and rapid prototyping of delivery systems with a variety of cargo molecules.
* Experience with assay development and miniaturisation.

Why AstraZeneca?
If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be. With us there are many opportunities to develop yourself and your career. From our diverse portfolio and teamwork, to our cutting-edge innovations - it's a place for lifelong learning.

So, what's next? Are you already imagining yourself joining us? Good, because we can't wait to hear from you! Welcome with your application no later than 8th August, 2021.

For more information about the position, please contact hiring manager Ulrika Tehler, Director, at ulrika.tehler(at)astrazeneca.com.

Additional information
BioPharmaceuticals R&D: https://www.youtube.com/watch?v=pmFx_jr2eFo
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/