Senior Scientist in Bioinformatics & Molecular Biology

Are you an enthusiastic scientist with experience in the field of molecular biology and bioinformatics with skills of recombinant protein expression? Are you looking to develop yourself and work together with a great team of scientists? Welcome to join our exciting journey at AstraZeneca!

At AstraZeneca in Gothenburg, Sweden we have a great opportunity open for a motivated Senior Scientist to join the Protein Expression & Molecular Biology Team within Discovery Biology, Discovery Sciences organisation. Leading from the bench, you will apply your skills in molecular biology, bioinformatics and recombinant protein expression with a passion for investigating scientific questions, combined with strong team working ethics, to drug discovery projects.

You will join our team whose remit is to support drug discovery projects globally with delivery of impactful recombinant protein reagents used for disease target identification and validation right through to clinical candidate evaluation. And as part of the broader Discovery Sciences organisation, you will be working within a vibrant scientific environment to support drug discovery. We push scientific advances in small molecules, oligonucleotides as well as other emerging technologies, always with a view to providing medicines to improve patient care.

Be encouraged and supported to think creatively in our dynamic environment. Here we are free from fear of failure, free to ask the right questions and make bold decisions.

What you will do:
This is a lab-based role, generating bespoke protein reagents to support technology development and projects in all phases of the discovery process. The role involves application of leading bioinformatic and molecular biology techniques to discover novel protein targets, design expression constructs, make DNA constructs for protein expression as well as troubleshooting.

In addition, you will be required to make a significant contribution to the development and application of novel science to advance our capabilities in the production of molecular biology tools used in early drug discovery.

Essential in the role:

* Master or Ph. D in Bioinformatics, Molecular Biology, Biotechnology, Cell Biology, Biochemistry or a related discipline, or 3 years of relevant working experience within Biotechnology.
* Experience in using bioinformatic tools and databases to identify novel proteins based on available target class information - and novel DNA nucleases or DNA modifying enzymes for genome editing applications.
* Experience in protein design to optimize function or performance in other applications, ie. crystallization.

We also see our new colleague as a person who thinks outside the box and find innovative scientific approaches and who holds enthusiasm and curiosity towards scientific questions and learning new skills. You can work in an independent and deliver-oriented way, but you also enjoy teamwork and have the ability to communicate and collaborate in a global setting with cross-functional groups. Previous experience in providing technical leadership and guidance to others is also a plus.

Desirable Requirements

* Skills in design of DNA construct for recombinant protein expression in prokaryotic and eukaryotic systems.
* Experience in cell culture for recombinant protein expression in a variety of prokaryotic and eukaryotic cell types, at scales from 1ml to 20L.
* Experience in use of automation equipment such as liquid handling platforms.
* Good understanding of drug discovery and how to contribute with scientific expertise within own area of expertise to drive project progression.

Why AstraZeneca?
Join the team that follows the science unlike anywhere else. This is the place for curious minds. Dig deep into the biology of complex disease and uncover breakthroughs. With more than 2,400 employees from over than 50 countries, our vibrant Gothenburg site is a truly inspiring place to work. Here, the history and future of scientific breakthrough come together. We believe that the diversity of our people is crucial to bringing new discoveries to life.

So, what's next? If this sounds like the job and place for you - welcome to apply!

We look forward to get to know you. Send your application as soon as possible, but no later than 18th September, 2022.

For more information about the position, please contact hiring manager Robert Roth at robert.roth@astrazeneca.com

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Make a move to Global Gothenburg: https://www.youtube.com/watch?v=c-Iqbb4aw38
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html