Senior Scientist - NGS for High-Throughput Transcriptomics

Job description
Are you an experienced Molecular Biologist with expertise in Next Generation Sequencing (NGS)? Do you wish to apply this knowledge in a role that is connected to our wider mission to show what science can do? If yes, we might have the role for you!


We seek a talented and highly engaged Molecular Biology/NGS scientist to join the Disease Molecular Profiling - NGS & Transcriptomics team at AstraZeneca in Gothenburg, Sweden. You will contribute with applying molecular biology and NGS expertise to our drug discovery portfolio and working on cutting edge technologies within the field.



Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.

Responsibilities
Work collaboratively with scientists from our team, different therapy areas, and computational biology to apply genomic technologies to further drug discovery.
Develop, evaluate, or implement customized NGS workflows for specific drug discovery projects.
Plan, design, run, enhance and troubleshoot existing NGS workflows such as bulk RNA-seq (e.g. mRNA-seq, totRNA-seq, ultra low-input) and high-throughput transcriptomics (e.g. 384-well-based methods).
Understand and interpret data analyzed by computational biology colleagues and communicate it effectively to project partners and stakeholders.
Keep records of all lab and technology development work and write technical reports and SOPs.
Effectively manage timelines and deliver projects according to deadlines.


Qualifications
Essential for the role:


Ph.D. degree or MSc with experience in Molecular Biology, Biotechnology, Biomedicine or in a relevant scientific discipline.
Hands-on lab-based experience in utilizing advanced molecular biology RNA-sequencing, DNA-sequencing or Epigenetic sequencing techniques.
This experience will cover all relevant aspects from hypothesis generation, through experimental design and execution, RNA and DNA extraction, sample and library preparation, sequencing (ideally with Illumina or Nanopore), data handling, post-sequencing QC and troubleshooting.
Scientifically-driven scientist with attention to details and excellent critical thinking skills.



Desirable for the role:


Background in applying a broad range of wet-lab techniques, such as mammalian cell-culture, high-throughput in-vitro drug testing, qPCR or automated liquid handling.
Working with laboratory automation / liquid handling systems, method and technology development and optimization.
Hands-on experience with Single Cell Transcriptomics or Spatial Transcriptomics.
Tissue dissection, single cell dissociation, microscopy, flow cytometry/FACS
Hands-on laboratory experience running NGS platforms (Illumina, Oxford Nanopore etc).
Sample Tracking by LIMS systems.



For us, it is important that all competence and skills in the labor market are utilized. We welcome all applicants and strive for diversity.

Application
2022-09-01, welcome with your application at www.randstad.se.


For more information contact: Malin Fridholm, malin.fridholm@randstad.se or Maria del Carmen Leiva Arrabal, maria.leiva@randstad.se.

About the company
Randstad Life Sciences specializes in the field of science and is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus!