Senior Scientist- Preclinical in vivo model generation

Are you an enthusiastic scientist with a passion for and experience in molecular and cell biology? Do you also possess practised knowledge of DNA cloning of a wide range techniques? If yes,

The Translational Genomics department at AstraZeneca in Gothenburg, Sweden, is growing and we have an exciting opening for a Senior Research Scientist to join our excellent Preclinical In Vivo Models team. The position is tailored for you that's a highly passionate and motivated molecular and cell biologist with extensive experience and innovative knowledge in the design and generation of DNA based constructs using a wide range of cloning techniques and their application in science & technology.

We continually push the boundaries of science to deliver medicines that treat diseases across our main therapy areas. Through our integration with Alexion, this now includes expanding the limits of scientific research to better understand rare diseases and to discover new life-changing treatments for them.

What you'll do:
You are a specialist in the area of molecular and cell biology and experienced in a variety of cloning techniques used for the generation of complex DNA constructs and their application in the development of advanced transgenic models. You will devise, champion and develop scientific areas aligned with project needs and be an authority in the area of molecular and cell biology and precise genome editing using both established and the latest techniques to lead projects from a lab-based perspective and to make significant contributions to the practical delivery of AstraZeneca project goals to arrange of therapeutic areas.

The role also includes you to provide disciplinary scientific expertise and propose experimental strategies, troubleshoot problems and make significant contributions to the delivery of projects in compliance with AstraZeneca corporate responsibility policies and relevant safety standards.

Essential for the role:
This role requires proven expertise on molecular and cell biology together with your scientific drive. You should have a Ph.D. degree or corresponding experience in a relevant scientific field or, alternatively, a first degree and significant relevant experience. As well as;

* Molecular biology expertise with extensive DNA cloning experience.
* Experience of working with Bacterial Homologous Recombination, Gibson assembly and Gateway cloning.
* Experience of working with cell culture.
* Experienced in confirmation assays of genetic manipulation.
* Working knowledge of the latest precise genome engineering tools such as CRISPR.
* An open and innovative mindset to contribute to the implementation of cutting edge in vivo models.
* Experience in the generation of scientific presentations and manuscripts for publication.

The person taking on this role also enjoys collaboration and team work - and have the skill to interact and communicate efficiently across interfaces of global functions and fields. This goes hand in hand with your problem-solving skills and strong delivery focus.

Desirable for the role:

* Experience of working with preclinical transgenic mouse models.
* Experience in drug discovery.

Why AstraZeneca?
Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment. Here we get to develop and grow - whether that's working at the leading-edge or on varied stages and molecules. Working on things that have never been done before.

So, what's next? If this sounds like your next challenge - welcome to apply today!

We look forward to your application no later than 27th February, 2022.

More information:
For more information about the position please contact hiring manager Katja Madeyski-Bengtsson at Katja.Madeyski-Bengtson@astrazeneca.com.

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Relocating to Gothenburg: https://www.astrazeneca.se/om-oss/verksamheten-i-sverige/goteborg/relocate-to-gothenburg.html
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html