Senior Scientist - Preclinical in vivo model generation

Do you title yourself as a passionate Senior Scientist with great expertise in molecular and cell biology? Do you also possess experience in the field of cloning techniques used for the generation of complex DNA constructs? If yes, this might be the next challenge for you!

Translational Genomics at AstraZeneca in Gothenburg, Sweden, have an exciting opportunity for motivated Senior Research Scientist to be part of the Preclinical In Vivo Models team. The position is available immediately for a highly skilled and motivated molecular and cell biologist with extensive experience and great knowledge in the design and generation of DNA based constructs using a wide range of cloning techniques and their application in science & technology.

Thrive in an energizing environment where challenging work goes hand in hand with development. With opportunities, recognition and bright minds, there's no better place to unlock learning and build a long-term career.

What you'll do:
You are an expert in molecular and cell biology, experienced in a variety of cloning techniques used for the generation of complex DNA constructs and their application in the development of advanced transgenic animal models. You will devise, champion and develop scientific areas aligned with project needs and be an authority in the area of molecular and cell biology and precise genome editing using both established and the latest techniques to lead projects from a lab-based perspective and to make significant contributions to the practical delivery of AstraZeneca project goals across a range of therapeutic areas.

You will provide disciplinary scientific expertise and will propose experimental strategies, troubleshoot problems and make significant contributions to the delivery of projects in compliance with AstraZeneca corporate responsibility policies and relevant safety standards.

Essential in the role:
You should have a Ph.D. degree or corresponding experience in a relevant scientific field or, alternatively, a first degree and significant relevant experience. As well as;

* Molecular biology expertise with extensive DNA cloning experience.
* Experience of working with Bacterial Homologous Recombination, Gibson assembly and Gateway cloning.
* Experience of working with cell culture.
* Experienced in confirmation assays of genetic manipulation.
* Working knowledge of the latest precise genome engineering tools such as CRISPR.
* An open and innovative attitude to contribute to the implementation of groundbreaking in vivo models.
* Experience in the generation of scientific presentations and manuscripts for publication.

We also believe that our new colleagues enjoys working in a collaborative environment and is a strong teammate. You should be able to work independently and have a positive, goal oriented and problem-solving attitude. Excellent English is required, both spoken and written.

Desirable in the role:

* Experience of working with preclinical transgenic mouse models.
* Experience in drug discovery.

Why AstraZeneca?
Be part of a dedicated Research & Development team. Fuelled by our commitment to help more patients, strengthen our pipeline and grow our area. If you walk our corridors, you will hear more English than Swedish - although a little Swedish will go a long way. Listen a while, and you'll hear that Gothenburg is a truly international and diverse environment - with over 50 nationalities on site.

What's next? If this sounds like a good opportunity to you - welcome to apply! Send your application as soon as possible but no later than 13th November, 2022.

For more information about the position, please contact hiring manager John Wiseman.

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Make a move to Global Gothenburg: https://www.youtube.com/watch?v=c-Iqbb4aw38