Senior Scientist - Protein production & Protein biochemistry

Are you truly passionate about the magic that happens in the lab and could see yourself applying your protein science knowledge in a successful pharmaceutical company? Would you like to join a team of highly skilled scientists where both your professional and personal skills are valued? If yes, this might be the spot for you!

We have an exciting opportunity for a Senior Scientist with protein science skills to join us, working within a dynamic scientific environment to support drug discovery. The Discovery Biology department within Discovery Sciences is responsible for the generation of novel reagents and assays to support projects in all phases of the drug discovery pipeline. We focus on scientific advances in small molecules, oligonucleotides and other new technologies and drug discovery platforms across our different core areas.

Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

What you will do:
You will be responsible for producing and characterizing recombinant proteins including enzymes, secreted proteins, transcription factors and proteins with less characterized functions. These proteins are used to enable drug discovery projects. Since this position is lab based, we expect that you get a lot of energy from being in the lab and have a true real passion for practical duties. We also want you to contribute to our specific field developments in the team.

In the daily work, we rely on you to deliver expertise in recombinant protein production and characterization, of different target class proteins. As well as work in partnership with global colleagues to ensure the delivery of high-quality protein reagents to projects and contribute with novel ideas and using discernment and knowledge where appropriate to influence project progression.

You will regularly work across functional boundaries to define what is needed for discovery projects and lead protein work to deliver to that. With your knowledge in a range of procedures relating to construct design, protein expression and purification of a diverse set of target proteins, you will plan and conduct laboratory projects and experimental strategies, develop methods and technologies, generate, interpret and report scientific data autonomously.

Essential in the role:

* PhD in biochemistry, biology or pharmacology or other a related field, or an MSc degree with significant relevant experience from pharmaceutical or biotechnology industry.
* Expertise and proven knowledge of a wide range of methods and technologies applied to the expression, purification and characterization of a diverse set of target proteins. E.g. construct design and protein engineering, bacterial expression, liquid chromatography, SDS-PAGE, mass spectrometry and biophysical techniques.

To be successful in this role you also need to enjoy collaboration and team work - and have the skill to interact and communicate efficiently across interfaces of global functions and fields in a multi-cultural settings. This goes hand in hand with your problem-solving and critical thinking skills, and strong delivery focus.

Desirable in the role:

* Target-class specific knowledge related to e.g. intrinsically disordered proteins, transcription factors or signaling proteins.
* Experience with high-throughput methods for protein purification at medium scale.
* Expertise in machine learning to predict protein expression.

Why AstraZeneca in Gothenburg?
Our Gothenburg site is one of AstraZeneca's three strategic R&D centres. Here, you'll feel a global atmosphere in a multinational environment. Collaboration comes in all forms - across teams, functions, countries and even companies. We nurture this collaboration and openness, by creating a site that has space for meetings, socialising and relaxation - where spontaneous moments can spark innovation.

So, what happens next? If this sounds like the job and place for you - apply today!

We look forward to get to know you better. Please send in your application as soon as possible, but no later than 25th September, 2022.

For more information about the position please contact hiring manager Lovisa Holmberg Schiavone at lovisa.holmberg.schiavone(at)astrazeneca.com.

Additional information:
Our AstraZeneca Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Make a move to Gothenburg: https://www.astrazeneca.se/om-oss/verksamheten-i-sverige/goteborg/relocate-to-gothenburg.html
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html