Senior Scientist – Stem Cell Engineering

AstraZeneca is now seeking a Senior Scientist – Stem Cell Engineering, location Gothenburg.

Are you an experienced scientist in the field of cell biology and advanced cell culture? Do you have understanding of molecular switches, cloning, gene engineering (CRISPR) and other technologies within synthetic biology that you are keen to apply for the development of novel cell-based therapies? Now you have the opportunity to join AstraZeneca in Gothenburg and be a key player in the build of Biopharmaceuticals R&D Cell Therapy department.

Purpose, Offer and Benefits

This role provides an opportunity to work in an international, highly cross disciplinary environment with ground-breaking techniques and technologies within areas such as stem cell biology and precise genome editing. You will work together with in vitro scientists and collaborate with disease area specialists, in vivo scientists and advanced imaging experts to develop scientific capabilities and ensure efficient progress of Cell Therapy projects.

The role is focused on laboratory-based activities and you will use your scientific expertise to design and execute experiments and to deliver high quality data. Your biggest impact will be through practical and scientific contributions to support projects in compliance with AstraZeneca corporate responsibility, policies and relevant safety standards.

At AstraZeneca, you will be empowered to be innovative and creative where difference is valued. We thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment. The role is placed at AstraZeneca´s dynamic R&D site in Gothenburg, Sweden, where you will work in an international setting at the fore front of Cell Therapy science.

Your Responsibilities

Accountability includes:

• Culture and differentiate pluripotent stem cells using small molecules/cytokines to physiological relevant cell types that can be used for cell therapy applications.
• Implement CRISPR, molecular switches and synthetic mRNA technologies in stem cells to improve the differentiation capacity.
• Implement receptor design and engineering strategies for immune cell types (e.g., CAR-T, CAR-M).
• Characterize and quantify cell phenotype/identity using readouts like qPCR, flow cytometry and imaging-based readouts.
• Develop and troubleshoot protocols for in vitro culture and differentiation of various cell types including pluripotent stem cells.
• Independently analyse and report data to support project decisions and communicate relevant information to project teams within the bioscience department as well as across other functions.

The Bigger Picture

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

This is a one-year consulting assignment, you will be employed by TNG during this time. 

Our Expectations

Essential for the role

• Ph.D. in Cell Biology or a related field with relevant academic or industrial experience.
• Experience with genome editing and developing reporter lines.
• Hands-on experience with mammalian cell culture and/or stem cell culture.
• Ability to work independently, take own initiatives and have a positive, goal oriented and problem-solving attitude
• Good organizational, data management and documentation skills
• Good scientific presentation skills and ability to comfortably present and discuss scientific data.

Interested?
This is a staffing assignment which means that you are employed by TNG, but work for one of our customers. If you are interested in this position, apply right now! The selection process is ongoing and the position can be filled before the last apply-date. If you have any questions, please contact the recruiter.