Senior Scientist Translational Genomics In Vivo Physiology

Translational Genomics In Vivo Physiology

Hays Life Sciences is now looking to recruit a Senior Research Scientist - Translational Genomics In Vivo Physiology for a 10-month contract assignment at AstraZeneca in Gothenburg.

The Discovery Sciences, Translational Genomics department is looking for a senior research scientist to be a part of our In vivo target validation team within the Transgenic Models team. The position is based at the AstraZeneca R&D site in Gothenburg, Sweden and we are seeking a scientific and technical specialist in the animal in vivo physiology field. As a successful candidate you are experimentally focused, with strong troubleshooting skills and adept at putting ideas into practice. By planning and performing animal experiments you will significantly contribute to the practical delivery of projects in compliance with AstraZeneca corporate responsibility policies and relevant safety standards. You will have good social and communication skills, be collaborative and be a strong team player. Candidates should further be able to work independently with a positive, goal oriented and problem-solving attitude. Good organizational skills are required, and you should be comfortable in presenting your results. Excellent English is required, both spoken and written.

Specific responsibilities

* Perform hands-on experiments within the in vivo target validation discipline, using behavioural and metabolic platforms to support all core disease areas
* Ensure that studies are conducted with high quality, dedication and data delivered according to stipulated time lines and project requirements
* Compile, interpret, present and discuss data with the key project teams
* Help out with ex vivo tissue culture experiments when needed

The following skills would be a definite advantage:

* Experience of behavioural phenotyping in mice
* Experience of stereotactic brain injections in mice
* Experience in metabolic phenotyping platforms and analysis of metabolic function in mice, for example indirect calorimetry, DEXA and oral glucose tolerance tests (OGTT)
* Use of viral vectors and non-viral delivery vehicles for in vivo genetic engineering

Minimum Requirements -Education and Experience
Ph.D. degree or corresponding experience in a relevant scientific discipline with expertise in phenotyping transgenic mice or, alternatively, a first degree and significant relevant experience in phenotyping of transgenic mice.