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Arbetsbeskrivning
At AstraZeneca we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.
Pharmaceutical Sciences at AstraZeneca delivers the therapies of the future through scientific leadership in drug delivery, design of synthetic routes, and manufacturing of Active Pharmaceutical Ingredients (API) and drug products. Advanced Drug Delivery (ADD) resides within Pharmaceutical Sciences with a mission to provide novel products to AstraZeneca's clinical pipeline. Our portfolio of projects spans traditional small molecules, peptides, oligonucleotides to RNA based therapeutics across AstraZeneca's therapy areas.
We are now recruiting two talented and motivated Senior Scientist/Scientist in the analytical and formulation areas to join our New Modality Preformulation team within the Advanced Drug Delivery (ADD) function in Gothenburg, Sweden. With more than 3000 employees from over 70 different countries, our vibrant Gothenburg site is a truly inspiring place to work.
What You'll do
This is an exciting role where you will act as a key member of various project teams and provide your technical and scientific expertise into formulation design and development strategiesfor novel biomacromoleculeswithin the newmodality area. As a Senior Scientist / Scientistyou will support drug projects from an analytical and formulation perspective in the discovery phase of the drug development process,working from target identification to candidate drug nomination.
The role covers development of formulations, analytical methods, characterization, and stability assessments of peptides, oligonucleotides, mRNA and other molecules of high complexity. You will support and lead drug projects within your own function in the preclinical phase and you will serve as a member of the cross-functional drug development project teams, representing your function and scientific area. You will work in close collaboration with formulation scientists, analytical chemists as well as biopharmaceutics experts in Gothenburg, Sweden but also with colleagues in Cambridge, UK and Waltham, US.
Essential for the roles
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Ph.D degree in relevant scientific discipline (e.g., Analytical Chemistry, Biochemistry, Biotechnology or Pharmacy) or 5+ years of industrial experience in the drug development phase.
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Previous experience of formulating or characterizing complex biomacromolecule (e.g. RNA, proteins and peptides) drug products.
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In-depth knowledge of analytical methodologies for oligonucleotides/RNA and peptide/protein characterization, with primary focus on size exclusion and liquid chromatography.
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Good understanding of formulation science, drug delivery and biopharmaceutics to enable mechanistic understanding of in vivo drug product performance.
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Scientific interest in exploratory formulation/analytical work related to complex molecules, delivery systems and new technologies.
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Ability and desire/willingness to effectively communicate, network and build collaborative relationships with partners across disciplines and cultures, internally and externally and independently lead and influence projects.
If your passion is science & technology and you want to be part of a team that makes a positive impact on patients' lives, then there's no better place to be. With us there are many opportunities to develop yourself and your career. From our diverse portfolio and teamwork to our cutting-edge innovations - it's a place for lifelong learning.
Are you ready to make a difference? Send in your application, and we'll make it happen together.
We encourage you to send your application as soon as possible, but no later than 26th of May, 2023
Additional information
Culture and atmosphere of the Gothenburg site
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