Senior Synthetic Chemist, New Modalities Chemistry

Are you a synthetic chemist with expertise in conjugation chemistry and targeted drug delivery? Would you like to apply your expertise in a company that is accelerating innovative science and turn ideas into life changing medicines? Join us to discover future treatment of Cardiovascular, Renal and Metabolic diseases!

Working at AstraZeneca means being entrepreneurial, thinking big and working together to make the impossible a reality. We are committed to the development of next generation innovative medicines and are currently expanding our teams focused on RNA therapeutics and Targeted Drug Delivery for the treatment of diseases across our therapy areas.

As part of this expansion, we are now recruiting a a skilled senior scientist with great passion in synthetic organic chemistry and a special interest in bridging chemistry across various modalities in the area of drug conjugates and targeted drug delivery. The position is placed at AstraZeneca's dynamic R&D site in Gothenburg, Sweden.

Cardiovascular, Renal and Metabolism (CVRM) is one of AstraZeneca´s core therapy areas. Together we push the boundaries of science to develop medicines that makes a true difference for patients suffering from Heart Failure, Diabetes or Chronic Kidney Disease.

The CVRM Medicinal Chemistry Department is an essential player in the discovery and design of drug molecules to identify and validate novel biological targets. We are proud of our successful delivery of clinical candidates to human testing leading to new medicines for patients. To realize our ambitions, we stay agnostic to molecular modality.

What you'll do

As a Senior Synthetic chemist, you will be part of an open minded, creative and experienced team where you will contribute with your high ambitions, collaborative attitude and enthusiasm to be part of design and synthesis of new candidate drugs. This is a lab-based role focused on medicinal chemistry with emphasis on synthetic chemistry of specific tissue targeting ligands and drug conjugates. You will actively contribute to AstraZeneca drug projects by compound design and synthesis, data generation and data interpretation. The work is done in a highly cross disciplinary environment in close collaboration with scientists from other functions like Bioscience, Discovery Sciences, DMPK and Pharmaceutical Sciences.

You are encouraged to be part of external collaborations, publish scientific papers, present and represent the department at scientific conferences.

Essential for the role

* Ph. D. degree in Organic Chemistry/Synthetic Chemistry/Drug Conjugate Chemistry or Medicinal Chemistry related to New Modalities. 2+-year relevant post-doctoral experience in academic or industrial setting preferred
* Expert knowledge in synthetic organic chemistry
* Experience of different modalities chemistry such a small molecules, peptides, RNA or drug conjugates is seen as an advantage
* Synthetic chemistry: ability to plan, prioritize and perform work independently including synthetic route design and problem solving
* Scientific creativity: ability to identify, develop and apply new technologies and ways of working
* Great awareness of recent literature within synthesis/medicinal chemistry as well as current developments and trends in organic synthesis
* Highly self-motivated and capable of receiving and analyzing input from complex data and deciding on focused course of action
* Excellent teamwork, collaboration, networking and communication skills
* Ability to communicate your work both to senior chemistry leaders and in scientific papers and documents
* Basic knowledge in medicinal chemistry or experience from drug discovery in an industrial setting is a plus but not essential.

So, what's next?

Are you already imagining yourself joining our team? Good, because we can't wait to hear from you!

For more information about the position please contact hiring manager Laurent Knerr, +46-31-776 10 00

Welcome with your application no later than June 17, 2020

Where can I find out more?

Our Gothenburg site: Link

Life in Gothenburg: Link

Culture and atmosphere of the Gothenburg site: Link

Meet Hasse, Chemist at AstraZeneca Gothenburg: Link

Why AstraZeneca?



Our Gothenburg site is one of AstraZeneca's three strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to foster a working environment that nurtures, collaboration, openness and innovation. Therefore, we have created space for meetings, socializing and relaxation, where spontaneous meetings can give birth to new innovations. The unexpected ideas or thoughts that can come from a chat over something as simple as a cup of coffee or a stroll on our "walk and talk" meeting trail.