Sr Research Scientist – on DNA synthesis

Do you have hands-on experience and knowledge of on-DNA chemistry? Are you interested to establish and develop new on-DNA chemistry and contribute to the delivery of DNA encoded libraries (DEL)? Join us at our DEL synthesis lab in a company where we are committed to lifelong learning, growth and development! Welcome to AstraZeneca!

We are seeking a driven Synthetic Chemist that will play an important part in our iLAB team, focusing on the on-DNA synthesis. You have the opportunity to contribute to the DEL synthesis capabilities in our new lab at AstraZeneca in Gothenburg and deliver on-DNA compounds as well as contribute to the validation of building blocks for the production of a proprietary compound collection based on DEL.

Responsibilities
This is an exciting role where you will contribute to the expansion of the new DEL synthesis lab capabilities at AstraZeneca Gothenburg. You will design and synthesize on-DNA compounds while also contributing to the continuous improvement of the DEL synthesis platform by evaluating new cutting edge synthetic approaches for on-DNA chemistry. You will also play a key role in validating new building blocks, extending the implementation of synthesis automation and in contributing to the improvement of our building blocks database.

In your daily work you will troubleshoot laboratory-based problems and make a significant contribution to the delivery of the team. As DEL Chemist, you will maintain access to the best internal and external science and enhance business reputation internally and externally through peer-reviewed publications and oral/poster presentations.

Your profile
Essential on the role:
You’re a chemist with a track record of applying innovative chemistry solutions, with resulting impact in project delivery. You also have:
• Ph.D. in a relevant chemistry discipline, or a Master degree in chemistry with minimum 5 years’ experience in synthetic organic chemistry.
• Expertise in synthetic organic chemistry, retrosynthesis, compound route design, purification and analysis.
• Knowledge of basic molecular biology techniques e.g gel electrophoresis, DNA ligation, PCR.
• Advanced knowledge of modern chemical literature, chemical technologies and applying new ideas to project delivery.
• A track record of driving innovation in chemistry related sciences.

The successful candidate should be motivated to work effectively in hardworking teams and demonstrate ability to work across scientific fields to get results. We also believe that our candidate have effective levels of communication, a scientific drive and a high interest in working with organic chemistry and molecular biology techniques.

Desirable in the role:
• Hands-on experience with on-DNA synthesis/DEL synthesis.

We also believe that the successful candidate have a detailed understanding of the chemical sciences and how they contribute and influence drug discovery together with knowledge of the drug discovery process.

About the organisation
This is a 1 year consultant assignement at AstraZeneca in Göteborg. During this time you will be hired by QRIOS. We work with Sweden’s leading pharmaceutical and life science companies. So whether you’re interested in research, regulatory affairs, quality assurance, environmental and quality control, sales and marketing, or just want a career change, we have the job for you.

Working as a consultant suits whoever wants to get a lot of experience in a short period of time. We offer you the chance to work with well-known brands at renowned companies where you can develop your skills. If you’re looking for a world of exciting assignments and new contacts, you’ll like being a consultant.

About Astra Zeneca:
AstraZeneca is a major international healthcare company engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. But we are more than one of the world’s leading pharmaceutical companies - at AstraZeneca, we are proud to have a unique culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.