Target Science in Early RIA Translational Science & Experimental Medicine

We have an exciting opportunity for a highly motivated Target Scientist within Early R&I Translational Science and Experimental Medicine at AstraZeneca. As Target Scientist, you will have an important role in the identification and validation of new innovative respiratory disease drug targets with the aim to achieve successful target selection investment decisions (TSID).

For further details around this 12-months consulting position you are welcome to contact Jenny Lundkvist at jenny.lundkvist@poolia.se.

Om tjänsten
Target Science within Early R&I Translational Science and Experimental Medicine is a fast-paced research environment, with a culture that is science-based and patient-focused. Our mission is to identify unique targets and mechanisms addressing the key biological drivers of chronic respiratory diseases enabling a precision medicine approach to treating patients. The aim is to enable early intervention to achieve durable remission and disease modification.

To deliver on this bold ambition, the Target Science team in R&I is continuously hunting for new respiratory targets, with a focus on novel sources such as genomics and functional phenotypic screening. We want to be able to target all cell types, mechanisms and pathways relevant to respiratory diseases by growing the druggable target space. We are leading the efforts focused on increasing the use of new modalities, including oligonucleotides, peptides, proteins and transcript therapy, in addition to conventional small molecules and antibody-based modalities.



Dina arbetsuppgifter i huvudsak
As Target Scientist, you will have an important role in the identification and validation of new innovative respiratory disease drug targets with the aim to achieve successful target selection investment decisions (TSID). This needs to be grounded in a proven and robust understanding of respiratory disease biology and disease relevant pathways and drivers at the molecular level.

Target Scientist is laboratory-based role, and you will work collaboratively with scientists from across Early R&I and supporting functions to generate new target ideas and develop them into data packages leading to positive TSID decisions. This includes the integration of complex data sets such as in vitro human cell/tissue, expression analysis, cell-based data, bioinformatics, genomics and in vivo data obtained through working with colleagues from other functions

Vem är du?
Qualifications & Skills:
• Excellent understanding of respiratory disease biology, including cell types, molecular pathways and mechanisms.
• Broad understanding of relevant target validation technologies and methodologies (e.g. PCR, Western Blotting, ELISA, FACS, microscopy, etc.) along with excellent scientific laboratory skills and ability to experimentally address key scientific questions.
• Ability to form hypotheses, test them experimentally, draw conclusions and suggest next steps based on the data.
• Ability to work productively in a matrix team environment and excellent collaborative skills.
• Excellent written, oral, presentation and interpersonal skills
• Good networking and communication (written and oral) skills and a strong delivery focus.

Education and experience:
• PhD or equivalent with a strong experimental drive and background in basic science related to respiratory research.
• Post-doc experience or otherwise relevant scientific research experience is an advantage.
• Previous experience from working in an industry environment is a plus, but not a requirement.

Om verksamheten
At AstraZeneca, we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.


Are you ready to bring new ideas and fresh thinking to the table? Brilliant!
We have one seat available and we hope it’s yours.