Target Scientist, AstraZeneca Gothenburg

Job description
Target Science within Early R&I Translational Science and Experimental Medicine is a fast-paced research environment, with a culture that is science-based and patient-focused. Our mission is to identify unique targets and mechanisms addressing the key biological drivers of chronic respiratory diseases enabling a precision medicine approach to treating patients. The aim is to enable early intervention to achieve durable remission and disease modification.

To deliver on this bold ambition, the Target Science team in R&I is continuously hunting for new respiratory targets, with a focus on novel sources such as genomics and functional phenotypic screening. We want to be able to target all cell types, mechanisms and pathways relevant to respiratory diseases by growing the druggable target space. We are leading the efforts focused on increasing the use of new modalities, including oligonucleotides, peptides, proteins and transcript therapy, in addition to conventional small molecules and antibody-based modalities.

Responsibilities
As Target Scientist, you will have an important role in the identification and validation of new innovative respiratory disease drug targets with the aim to achieve successful target selection investment decisions (TSID). This needs to be grounded in a proven and robust understanding of respiratory disease biology and disease relevant pathways and drivers at the molecular level.

Target Scientist is laboratory-based role, and you will work collaboratively with scientists from across Early R&I and supporting functions to generate new target ideas and develop them into data packages leading to positive TSID decisions. This includes the integration of complex data sets such as in vitro human cell/tissue, expression analysis, cell-based data, bioinformatics, genomics and in vivo data obtained through working with colleagues from other functions. This is a consultant assignment at AstraZeneca, Gothenburg.

Qualifications
Qualifications & Skills
Excellent understanding of respiratory disease biology, including cell types, molecular pathways and mechanisms.
Broad understanding of relevant target validation technologies and methodologies (e.g. PCR, Western Blotting, ELISA, FACS, microscopy, etc.) along with excellent scientific laboratory skills and ability to experimentally address key scientific questions.
Ability to form hypotheses, test them experimentally, draw conclusions and suggest next steps based on the data.
Ability to work productively in a matrix team environment and excellent collaborative skills.
Excellent written, oral, presentation and interpersonal skills
Good networking and communication (written and oral) skills and a strong delivery focus.

Education and experience
PhD or equivalent with a strong experimental drive and background in basic science related to respiratory research.
Post-doc experience or otherwise relevant scientific research experience is an advantage.
Previous experience from working in an industry environment is a plus, but not a requirement.

For us, it is important that all competence and skills in the labor market are utilized. We welcome all applicants and strive for diversity.

Application
2020-12-10, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.


For more information: Galia Nyström Askarieh, galia.nystrom@randstad.se or Eleonor Ehrman, +46733434109

About the company
Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.

Randstad Life Sciences is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus!