Thesis work: Cigarette smoke exposure to 3D epithelial cells

Job description
Direct cigarette smoke exposure to 3D epithelial cell cultures by VC10-S robot.
Thesis project: 30 credits

Cigarette smoke is the main driver of COPD, the third most common cause of death worldwide. The disease is characterized by destruction of the airways and inflammation. In this project we aim to establish a method for direct exposure of 3D cultures of airway epithelial cells to cigarette smoke by an advanced robotic system.

At AstraZeneca, we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

Responsibilities
In this placement, the student will be part of a cross-functional team within Research and Early Development, Respiratory, Inflammation and Autoimmune (RIA) department building scientific knowledge around disease-causing mechanisms and identification of novel targets for treatment. Specifically, the student will be working closely with a team with high expertise in epithelial cell cultures.

Objectives and goals
Establish protocol for exposure of epithelial cells to direct cigarette smoke.
Get insight in project work. 
Contribute scientifically to the Bioscience and Target Science teams. 
Acquire experience in machine systems operation as well as molecular and cell biology methods including MSD, ELISA and confocal microscopy. 


Qualifications
Essential Requirements 
 Good networking skills and interpersonal skills.
 Interest and curiosity in technical equipment.
 Ability to work independently.
 Understanding of cell biology and molecular biology.
 Written and oral communication skills in English.


Desirable Requirements 
 Experience in cell culture.
 Skilled in problem solving.


Application
Randstad Life Sciences is cooperating with AstraZeneca in this recruitment process. We only accept applications through Randstad’s website.

Deadline for application: 2020-03-31, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.

For more information: Kerstin Karlsson kerstin.karlsson@randstad.se or Eleonor Ehrman +4673-343 41 09.

About the company
Our Gothenburg site is one of AstraZeneca's three strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to foster a working environment that nurtures, collaboration, openness and innovation. Therefore, we have created space for meetings, socializing and relaxation, where spontaneous meetings can give birth to new innovations. The unexpected ideas or thoughts that can come from a chat over something as simple as a cup of coffee or a stroll on our “walk and talk” meeting trail.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.