thesis work: clinical pharmacology and pharmacokinetics

Arbetsbeskrivning
Thesis work: clinical pharmacology and pharmacokinetics with focus on drug development in treatment of respiratory disease 


If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do – join us!


Thesis type: 30 credits
Project start: August 2023
Student location: On Site, Gothenburg Sweden

Do you have interest, and passion for, Pharmacokinetics, Drug-Drug interactions, Metabolism and Clinical Drug Development? Then a master thesis at Astra Zeneca in Gothenburg within Clinical Pharmacology and Quantitative Pharmacology might be of interest to you! We are a group of Clinical Pharmacology and Pharmacometric scientists with expertise in clinical pharmacokinetics, pharmacodynamics and modeling who work with respiratory and inflammatory diseases such as asthma and COPD. We would like support with the following project: 


Map out a typical patient with a respiratory disease for one of our new treatments. The purpose of the project would be to gain a deeper understanding of the following key areas: 


What drugs is currently prescribed to a typical patient with this disease, today and in the future? 
Of the prescribed medicines, which are the most problematic from a drug-drug interaction perspective? 
What other diseases are common in the patient group? What more do we know of the patients in terms of liver function, renal function, and age?  


At AstraZeneca, all of our employees make a difference to patients’ lives every day. We operate in more than 100 countries around the world and are one of Sweden’s most important export companies.


With more than 2,400 employees from 50 countries, the vibrant Gothenburg site helps to support the entire life-cycle of AstraZeneca medicines, from drug discovery and clinical trials, to global commercialisation and product maintenance. Gothenburg is one of AstraZeneca’s three strategic, global R&D centres, alongside Cambridge and Gaithersburg, and plays a central role in our mission to deliver life-changing medicines to patients.


Randstad Life Sciences is collaborating with AstraZeneca in this recruitment process. Please send your application in English and we only accept applications through Randstad’s website.


Deadline for application: 2023-04-16, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.


 For us, it is important that all competence and skills in the labor market are utilized. We welcome all applicants and strive for diversity.



Ansvarsområden
The purpose with this analysis would be to improve our understanding of how to plan clinical studies and drug development programs to ensure that we can always give good recommendations to prescribers, pharmacists and patients about dose and dose adjustments for new treatments. 


Methods: Database and literature searches. Summarize and conclude on the research. Basic pharmacokinetic assessments and statistical analysis. Illustration and presentation. Prepare analysis plan and report. Advantage if the work is done in English. 


You will be supervised by a mentor who works in clinical drug development to develop new medicines for patients with respiratory and inflammation disease and who is a specialist in clinical pharmacokinetics, modeling, drug-drug interactions and who works in the Clinical Pharmacology and Quantitative Pharmacology Team. 

Kvalifikationer
Pharmacy or engineer student or similar on a master level
Interested in the project and can independently search scientific literature and want to go deeper in specific areas to understand relationships and patterns 
Good at oral and written presentation (Swedish or English)
Can do basic pharmacokinetic calculations and descriptive statistics 




Om företaget
If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do – join us! 


At AstraZeneca we are guided in our work by a strong set of values, and we’re resetting expectations of what a bio-pharmaceutical company can be. By truly following the science, we pioneer new methods, new thinking and bring unexpected teams together. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that transform lives. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world. If you’re swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.


AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.