Thesis work: NGS-based High-Throughput Transcriptomics profiling

Job description
 NGS-based High-Throughput Transcriptomics profiling 

Thesis type: 60 credits
Project start: January 2023
Student location: On Site, Gothenburg Sweden

Are you a scientist or an engineer with interest in Molecular Biology and Next Generation Sequencing (NGS)? Would you like to apply your expertise and gain this knowledge to impact the technology strategy in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be of interest to you! 
 
We are looking for a self-motivated and engaged master student for a thesis project work within the Disease Molecular Profiling - NGS & Transcriptomics function at AstraZeneca in Gothenburg, Sweden. 

Responsibilities
This is an exciting opportunity to learn and apply cutting edge NGS/Transcriptomics technologies, understand the drug discovery process, and collaborate with world-class scientists across AstraZeneca’s R&D sites.

What you will do:
Evaluate, and implement customized NGS workflows for specific drug discovery projects.
Plan, design, run, enhance and troubleshoot existing NGS workflows such as bulk RNA-seq (e.g. mRNA-seq, totRNA-seq, ultra low-input) and high-throughput transcriptomics (e.g. 384-well-based methods).
Understand and interpret data analyzed by computational biology colleagues and communicate it effectively to project partners and stakeholders.
Keep records of all lab and technology development work and write technical reports and SOPs.


Qualifications
Essential Requirements 
Currently enrolled as a student within a scientific or technical field 
Experience in molecular biology 
A strong interest in drug discovery and the pharmaceutical industry 
Written and oral communication skills in English
Ability to work collaboratively and independently

Desirable Requirements 
Knowledge in Next Generation Sequencing (NGS)  
A wet-lab experience in some molecular biology techniques (e.g. nucleic acid extraction, PCR/qPCR).
Experience in cell culturing


About the company
At AstraZeneca, all of our employees make a difference to patients’ lives every day. We operate in more than 100 countries around the world and are one of Sweden’s most important export companies. With more than 2,400 employees from 50 countries, the vibrant Gothenburg site helps to support the entire life-cycle of AstraZeneca medicines, from drug discovery and clinical trials, to global commercialisation and product maintenance. Gothenburg is one of AstraZeneca’s three strategic, global R&D centres, alongside Cambridge and Gaithersburg, and plays a central role in our mission to deliver life-changing medicines to patients.