Toxicology Project Lead

Are you passionate about working for a global pharmaceutical company who truly puts patients first? Would you like to apply your toxicology expertise in a company that is accelerating innovative science and turns ideas into life changing medicines? Welcome to join AstraZeneca!

We are looking to recruit an experienced Toxicology Project Lead to join our Safety team discovering and developing medicines in the Cardiovascular, Renal, and Metabolic Therapy Area. The position may be placed either at our vibrant R&D site in Gothenburg, Sweden or at our US headquarters in Gaithersburg, Maryland US. In this role you will be a part of the Clinical Pharmacology and Safety Sciences (CPSS) organisation within BioPharma R&D.

What you will do:
In this position you will work at the forefront of toxicology and safety science, working in a multidisciplinary environment where you will play a key role in progressing a rich and diverse pipeline that includes small molecules, cutting-edge mAb-based therapeutics, oligonucleotides, and next generation cellular and viral therapies. You will combine your experience in toxicology and drug development with strong communication and interpersonal skills to communicate across all levels of internal and external stakeholders.

Your main responsibilities will involve:

* Designing and interpreting toxicology research programs to enable clinical development and marketing of our medicines and the authorship of quality regulatory documents (e.g. clinical trial and marketing applications)
* Leading the toxicology input to AstraZeneca project teams and interacting with external health authorities. You will operate across international boundaries within CPSS and across R&D functions in AstraZeneca to lead and manage projects and stakeholders
* Exploring drug project safety risks and developing risk mitigation strategies by combining data from traditional toxicological methods with data from more novel approaches and computational tools to build mechanistic understanding
* Providing expert nonclinical evaluation of in-licensing and out-licensing opportunities
* Contributing to the delivery of the departmental strategy and objectives

Essentials for the role:

* A PhD, or advanced university degree with relevant experience in Toxicology or equivalent life-science subject is required.
* Experience with the design, execution, and interpretation of toxicology studies conducted in support of pharmaceutical project development and knowledge of Good Laboratory Practice (GLP) regulations and regulatory agency guidelines.
* Experience delivering toxicology risk assessments within a pharmaceutical project environment, preferably within the therapeutic space of cardiovascular, renal, and/or metabolic diseases.
* Strong communication, presentation, and influencing skills.
* Strong project leadership skills with an ability to collaborate and operate with sensitivity and flexibility in a matrix project environment.
* Willingness to challenge conventional thinking and implement creative ideas balanced with a high regard and understanding for the regulatory framework in which AstraZeneca operates

We also believe that the successful candidate has a social personality with strong inter-personal skills that contributes to our team culture in which trust, cooperative support, diversity, and inclusion enable engaged and motivated colleagues to deliver and develop.

The level of the role will be decided depending on your experiences.

Why AstraZeneca?
AstraZeneca is a global, science-driven biopharmaceutical company - where we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. AstraZeneca is proud to provide a unique workplace culture that inspires innovation and cross-boundary collaboration. Within this environment employees are empowered to express diverse perspectives, and are made to feel valued, energized and rewarded for their ideas and creativity.

If you are a Toxicology Project Lead with experience in the development of pharmaceuticals we would like to hear from you - apply now!

We look forward to your application, please send it to us no later than January 8th, 2021.

For more information about the position please contact Ulf Andersson, Head of CVRM Safety, ulf.andersson@astrazeneca.com.